Scientists Urge UN to Take Action on Chemicals in Consumer Products and Pesticides

A group of influential scientists have called for swift action by the UN to prevent harm from a wide variety of synthetic chemicals in consumer products and pesticides that play a role in increased incidences of reproductive diseases, cancer, obesity, and type-2 diabetes worldwide.

The scientists include authors of a recent report by the World Health Organization (WHO) and the United Nations Environment Program (UNEP), which underlines the urgent need for global action to address the dangers of hormone or endocrine disrupting chemicals (EDCs).

The scientists’ statement is part of a growing international effort to identify and control the harmful effects of chemicals that damage hormonal (endocrine) systems in humans and wildlife that is supported by more than 100 countries engaged in a process to develop a global plan for the safe management of chemicals.

“Exposure to EDCs during fetal development and puberty plays a role in the increased incidences of reproductive disease, endocrine-related cancers, behavioral and learning problems including ADHD, infections, asthma and perhaps obesity and diabetes in humans,” said William F. Young, Jr., MD, president of The Endocrine Society, the most active organization devoted to research on hormones and the clinical practice of endocrinology. The Society’s 2009 Scientific Statement on EDCs was the first in-depth scientific report to draw attention to the unique properties of these chemicals, and the Society and its members remain active in advancing endocrine science and the knowledge of how EDCs affect health.

EDCs are commonly found in food and food containers, plastic products, furniture, toys, carpeting, building materials, and cosmetics. EDCs include chemicals such as bisphenol A (water bottles, can linings), certain phthalates (various plastic products and cosmetics), and pesticides such as chlorpyrifos (used on a wide variety of food crops). They are often released from the products that contain them and enter the bodies of humans and wildlife through dust or through the food chain. Tests show the presence of dozens of chemicals with hormone disrupting properties in people, including developing children. Manufacturers of suspected EDCs include some of the world’s largest chemical manufacturers, such as Exxon Mobil, Dow, DuPont, BASF, Monsanto, Eastman Chemical, and others.

In their letter addressed to UNEP, WHO, Organization for Economic Cooperation and Development (OECD) and the Strategic Approach to International Chemicals Management (SAICM), the scientists recommended a number of key principles, supported by current scientific research, to guide upcoming efforts in this area.

A clear definition of EDCs. Endocrine disrupting chemicals are chemicals, or chemical mixtures, that interfere with normal hormone action.

Vulnerability of living organisms. Hormones and their signaling pathways are critical for normal functioning in all vertebrates and invertebrates.

EDCs effects occur at low doses. Many EDC effects occur at low doses even when high dose effects are not apparent.

EDCs can affect future generations and timing of exposure is key. The most sensitive period is during periods of development, from the fetal and post-natal periods, which can extend into infancy and childhood for some tissues.

Exposure to EDC mixtures may be different than exposure to single substances. Humans and animals are exposed to complex mixtures of hundreds of EDCs.

The Precautionary Principle is key. Decision-making should err on the side of precaution.
“EDCs present unacceptable risks to human health and the environment, and that is why more than 100 governments reached consensus agreement that action is needed,” said Olga Speranskaya, co-chair, IPEN. “In our letter, we outline the most important principles for actions on EDCs. We urge the international agencies to utilize these principles as the basis for moving forward as quickly as possible.”

A recent report from WHO and UNEP, State of the Science of Endocrine Disrupting Chemicals, 2012, said that recent increases in the incidence of endocrine-related diseases in people and wildlife cannot be explained by genetics alone and that EDCs are a “global threat that needs to be resolved.” A recent editorial in Environmental Health Perspectives, a leading, peer-reviewed journal, identified EDCs as a global problem requiring global solutions. And more than 100 countries participating in an international process for implementing a global safe chemicals management plan (SAICM) reached consensus agreement that EDCs are an emerging issue requiring capacity building and awareness-raising and the translation of research results into control actions.

-------------------------------------------------------------------
For more stories on health, pollution, chemical exposure and improving your indoor air quality visit www.allerair.com or call to speak to an air quality expert about improving the air in your home 1-888-852-8247.

AllerAir Air Purifiers remove 99.97% of airborne dust, particles and the chemicals and odors that other air cleaners leave behind.

Effects of human exposure to hormone-disrupting chemicals examined in landmark UN report

Many synthetic chemicals, untested for their disrupting effects on the hormone system, could have significant health implications according to the State of the Science of Endocrine Disrupting Chemicals, a new report by the United Nations Environment Programme (UNEP) and WHO.

The joint study calls for more research to understand fully the associations between endocrine disrupting chemicals (EDCs)—found in many household and industrial products—and specific diseases and disorders. The report notes that with more comprehensive assessments and better testing methods, potential disease risks could be reduced, with substantial savings to public health.

Some substances can alter the hormonal system

Human health depends on a well-functioning endocrine system to regulate the release of certain hormones that are essential for functions such as metabolism, growth and development, sleep and mood. Some substances known as endocrine disruptors can alter the function(s) of this hormonal system increasing the risk of adverse health effects. Some EDCs occur naturally, while synthetic varieties can be found in pesticides, electronics, personal care products and cosmetics. They can also be found as additives or contaminants in food.

The UN study, which is the most comprehensive report on EDCs to date, highlights some associations between exposure to EDCs and health problems including the potential for such chemicals to contribute to the development of non-descended testes in young males, breast cancer in women, prostate cancer in men, developmental effects on the nervous system in children, attention deficit /hyperactivity in children and thyroid cancer.

Human exposure can occur in a number of ways

EDCs can enter the environment mainly through industrial and urban discharges, agricultural run-off and the burning and release of waste. Human exposure can occur via the ingestion of food, dust and water, inhalation of gases and particles in the air, and skin contact.

“Chemical products are increasingly part of modern life and support many national economies, but the unsound management of chemicals challenges the achievement of key development goals, and sustainable development for all,” said UN Under Secretary-General and UNEP Executive Director Achim Steiner.

“Investing in new testing methods and research can enhance understanding of the costs of exposure to EDCs, and assist in reducing risks, maximizing benefits and spotlighting more intelligent options and alternatives that reflect a transition to a green economy,” added Mr Steiner.

More research is needed

In addition to chemical exposure, other environmental and non-genetic factors such as age and nutrition could be among the reasons for any observed increases in disease and disorders. But pinpointing exact causes and effects is extremely difficult due to wide gaps in knowledge.

“We urgently need more research to obtain a fuller picture of the health and environment impacts of endocrine disruptors,” said Dr Maria Neira, WHO’s Director for Public Health and Environment. “The latest science shows that communities across the globe are being exposed to EDCs, and their associated risks. WHO will work with partners to establish research priorities to investigate links to EDCs and human health impacts in order to mitigate the risks. We all have a responsibility to protect future generations."

The report also raises similar concerns on the impact of EDCs on wildlife. In Alaska in the United States, exposure to such chemicals may contribute to reproductive defects, infertility and antler malformation in some deer populations. Population declines in species of otters and sea lions may also be partially due to their exposure to diverse mixtures of PCBs, the insecticide DDT, other persistent organic pollutants, and metals such as mercury. Meanwhile, bans and restrictions on the use of EDCs have been associated with the recovery of wildlife populations and a reduction in health problems.

Recommendations

The study makes a number of recommendations to improve global knowledge of these chemicals, reduce potential disease risks, and cut related costs. These include:

• Testing: known EDCs are only the ‘tip of the iceberg’ and more comprehensive testing methods are required to identify other possible endocrine disruptors, their sources, and routes of exposure.
• Research: more scientific evidence is needed to identify the effects of mixtures of EDCs on humans and wildlife (mainly from industrial by-products) to which humans and wildlife are increasingly exposed.
• Reporting: many sources of EDCs are not known because of insufficient reporting and information on chemicals in products, materials and goods.
• Collaboration: more data sharing between scientists and between countries can fill gaps in data, primarily in developing countries and emerging economies.

“Research has made great strides in the last ten years showing endocrine disruption to be far more extensive and complicated than realized a decade ago,” said Professor Åke Bergman of Stockholm University and Chief Editor of the report. “As science continues to advance, it is time for both management of endocrine disrupting chemicals and further research on exposure and effects of these chemicals in wildlife and humans.”