Study: Exposure to tobacco smoke residue on surfaces just as bad as breathing it in.

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Third-hand smoke is just as deadly as first-hand smoke, says a scientist at the University of California, Riverside who, along with colleagues, conducted the first animal study of the effects of third-hand smoke.
While first-hand smoke refers to the smoke inhaled by a smoker and second-hand smoke to the exhaled smoke and other substances emanating from a burning cigarette that can get inhaled by others, third-hand smoke is the second-hand smoke that gets left on the surfaces of objects, ages over time and becomes progressively more toxic.

“We studied, on mice, the effects of third-hand smoke on several organ systems under conditions that simulated third-hand smoke exposure of humans,” said Manuela Martins-Green, a professor of cell biology who led the study.  “We found significant damage occurs in the liver and lung. Wounds in these mice took longer to heal.  Further, these mice displayed hyperactivity.”

The results of the study provide a basis for studies on the toxic effects of third-hand smoke in humans and serve to inform potential regulatory policies aimed at preventing involuntary exposure to third-hand smoke.

Third-hand smoke is a potential health threat to children, spouses of smokers and workers in environments where smoking is, or has been, allowed. Contamination of the homes of smokers by third-hand smoke is high, both on surfaces and in dust, including children’s bedrooms.  Re-emission of nicotine from contaminated indoor surfaces in these households can lead to nicotine exposure levels similar to that of smoking. Third-hand smoke, which contains strong carcinogens, has been found to persist in houses, apartments and hotel rooms after smokers move out.

The  team was surprised to find that the damage caused by third-hand smoke extends to several organs in the body.

“More recently we have found that exposure to third-hand smoke results in changes that can lead to type II diabetes even when the person is not obese,” Martins-Green said. “There is still much to learn about the specific mechanisms by which cigarette smoke residues harm nonsmokers, but that there is such an effect is now clear.  Children in environments where smoking is, or has been allowed, are at significant risk for suffering from multiple short-term and longer health problems, many of which may not manifest fully until later in life.”

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